Product Description
Shearing and clean-up in one order keeps fragmentation workflows moving. This Zymo Research bundle pairs dsDNA Shearase Plus with a matching DCC-5 (DNA Clean & Concentrator-5) kit, so DNA can be enzymatically fragmented and then purified without sourcing separate products. It is a convenient choice for labs wanting a complete solution.
This listing is for catalog number E2019-50: dsDNA Shearase Plus, 50 U. The endonuclease cleaves phosphodiester bonds with a strong preference for dsDNA, producing random-ended fragments with 5'-phosphate and 3'-hydroxyl termini at the desired size in a single step. Its low-volume compatibility limits sample loss, and the included clean-up kit removes enzyme and buffer afterward. Available in 50 U and 200 U enzyme sizes. Order it from LIGHT LABS and keep your workflow moving.
Key Features
- Enzyme plus clean-up – Includes a matching DNA Clean & Concentrator-5 kit.
- Enzymatic shearing – Fragments DNA without sonication equipment.
- dsDNA preference – Strongly favors double-stranded DNA.
- Random-ended fragments – Generates fragments of the desired size in one step.
- Low-volume compatible – Minimizes sample loss.
Specifications
| Catalog Number | E2019-50 |
| Brand | Zymo Research |
| Description | dsDNA Shearase Plus, 50 U |
| Sizes | 50 U; 200 U |
| Included | Matching DCC-5 kit |
| Ends produced | 5'-phosphate and 3'-hydroxyl |
| Procedure | Single step |
| Shipping Conditions | Ships on dry ice |
| Storage | -80C, Room Temperature |
Available Sizes & Components
Applications
- NGS library preparation
- Methylation analysis fragmentation
- ChIP and MeDIP workflows
- Low-input DNA shearing
