Product Description
Distinguishing 5-hydroxymethylcytosine from 5-methylcytosine is central to many epigenetics studies. This Zymo Research enzyme specifically tags 5-hmC in DNA with a glucose group, creating a modified base that downstream methods can recognize and measure. It provides a key labeling step for many 5-hmC detection strategies used in epigenetics research.
This listing is for catalog number E2026: 5-hmC Glucosyltransferase, 100 U. The highly active glucosyltransferase converts 5-hmC to glucosyl-5-hydroxymethylcytosine, which can then be used for sequence-specific, genome-wide or global 5-hmC detection. It fits into restriction-based, enrichment and sequencing approaches that rely on glucosylation. Available in 100 U and 200 U sizes. Its specificity helps separate 5-hmC signal from 5-mC. LIGHT LABS ships genuine Zymo Research products with knowledgeable support from our Englewood, Colorado team.
Key Features
- 5-hmC specific – Selectively tags 5-hydroxymethylcytosine.
- Glucose labeling – Produces glucosyl-5-hydroxymethylcytosine.
- Highly active – Efficient enzymatic conversion.
- Flexible detection – Supports sequence-specific, genome-wide or global 5-hmC analysis.
- Two sizes – Available in 100 U and 200 U.
Specifications
| Catalog Number | E2026 |
| Brand | Zymo Research |
| Description | 5-hmC Glucosyltransferase, 100 U |
| Sizes | 100 U; 200 U |
| Substrate | 5-hydroxymethylcytosine in DNA |
| Product | Glucosyl-5-hydroxymethylcytosine |
| Shipping Conditions | Ships on dry ice |
| Storage | -80°C |
Available Sizes & Components
Applications
- 5-hmC detection and quantification
- Hydroxymethylation mapping
- Epigenetics research
- Distinguishing 5-hmC from 5-mC
