Product Description
Archived FFPE blocks hold years of clinical and research value, but formalin crosslinks make their RNA hard to recover. This Zymo Research kit offers a dependable route to total RNA from formalin-fixed, paraffin-embedded tissue, with chemistry tuned to recover both large transcripts and small RNAs from these challenging samples.
This listing is for catalog number R1008: Quick-RNA FFPE MiniPrep, 50 Preps. The workflow is straightforward: remove paraffin with the included Deparaffinization Solution, digest the tissue with Proteinase K, apply heat to reverse crosslinks, and purify on a Zymo-Spin column. The eluted total RNA, including small RNAs of 17 to 200 nt, is DNA-free and ready for RT-PCR, hybridization and sequencing. Each kit provides 50 preps. Add it to your LIGHT LABS order and keep your bench stocked.
Key Features
- Optimized for FFPE – Chemistry designed to maximize RNA recovery from fixed, embedded tissue.
- Captures small RNAs – Recovers total RNA including species of 17 to 200 nt.
- Crosslink reversal – A heat step helps release RNA from formalin modifications.
- DNA-free output – Purified RNA is free of genomic DNA for clean downstream results.
- Simple spin-column format – Deparaffinize, digest, heat and purify in one workflow.
Specifications
| Catalog Number | R1008 |
| Brand | Zymo Research |
| Description | Quick-RNA FFPE MiniPrep, 50 Preps |
| Sample type | Formalin-fixed, paraffin-embedded (FFPE) tissue |
| RNA recovered | Total RNA including small RNAs (17–200 nt) |
| DNA removal | DNA-free RNA |
| Format | Zymo-Spin column |
| Prep size | 50 preps |
| Shipping Conditions | Ships at room temperature |
| Storage | Room Temperature |
Applications
- RT-PCR and RT-qPCR on archival tissue
- RNA sequencing of FFPE samples
- miRNA analysis from FFPE blocks
- Retrospective clinical research
- Tumor gene expression profiling
