Product Description
Measuring global DNA methylation by chromatography starts with breaking DNA down to single nucleotides. This Zymo Research nuclease mix does that quickly and efficiently in one step, offering a faster and simpler alternative to multi-enzyme digestion protocols. It helps epigenetics labs measure total DNA methylation with less hands-on time.
This listing is for catalog number E2016: DNA Degradase, 500 U. The enzyme blend degrades DNA completely into its individual nucleotide components, producing material ready for whole-genome methylation analysis by HPLC, TLC and other methods. A single-step digestion keeps hands-on time low. It is available in 500 U and 2000 U sizes. The streamlined digestion improves consistency between samples. LIGHT LABS ships genuine Zymo Research products with knowledgeable support from our Englewood, Colorado team.
Key Features
- Complete digestion – Breaks DNA into individual nucleotides.
- One-step procedure – Faster and simpler than multi-step digestion methods.
- Nuclease mix – Blended enzymes ensure efficient degradation.
- Methylation analysis ready – Suited to HPLC, TLC and similar techniques.
- Two sizes – Available in 500 U and 2000 U.
Specifications
| Catalog Number | E2016 |
| Brand | Zymo Research |
| Description | DNA Degradase, 500 U |
| Sizes | 500 U; 2000 U |
| Product | Individual nucleotides |
| Procedure | One-step digestion |
| Downstream use | HPLC, TLC |
| Shipping Conditions | Ships on dry ice |
| Storage | -80°C |
Available Sizes & Components
Applications
- Global DNA methylation analysis
- HPLC nucleotide analysis
- TLC-based methylation assays
- DNA composition studies
