Excel Scientific AlumaSeal® 384™ F-384-100 Aluminum Foil Seal for 384-Well Plates, PCR & Cold Storage, Non-Sterile — 100/Pack

Product Description

The Excel Scientific AlumaSeal® 384™ F-384-100 is a pierceable aluminum foil microplate sealing film specifically dimensioned for 384-well plates — delivering reliable sealing for PCR thermal cycling and cold storage at -80°C in the high-density plate format used by high-throughput screening, compound management, and genomics workflows. AlumaSeal 384 sealing films have one end tab with no perforations. Pierceable. Available non-sterile only. Sealing film dimensions are 137.3 mm × 82.5 mm (including single 13.5 mm end tab). Certified DNase-free, RNase-free, and nucleic acid-free. 100 foil seals per pack.

Specifically Dimensioned for 384-Well Plates The F-384-100 is sized precisely for 384-well microplates — one of the most widely used high-density plate formats in HTS, compound library management, genomics, and qPCR workflows. The 137.3 × 82.5mm dimensions provide sufficient sealing area to cover all 384 wells with a secure, uniform foil seal that minimizes evaporation, prevents cross-contamination between wells, and protects samples from light and atmospheric contamination. For 96-well plates, see the F-96-100 (AlumaSeal® 96™) which is sized for raised-rim 96-well plates.

PCR and Cold Storage — Both Supported The AlumaSeal® 384™ supports both PCR thermal cycling and cold storage at -80°C — a critical advantage for HTS labs that run 384-well plate PCR assays and also require sealed plate storage at ultra-low temperatures between processing steps. A single foil seal type covers the complete workflow from thermal cycling through frozen storage without requiring separate seal inventories for each application.

Pierceable — Robotic Probe and Pipette Tip Compatible The aluminum foil construction of the F-384-100 is pierceable with standard pipette tips and robotic liquid handling probes — allowing direct well access for sample addition and retrieval in automated workflows without removing the seal. This is essential for 384-well compound management and HTS workflows where robotic probes must access individual wells while the plate remains sealed, and where manually removing and replacing foil seals between each access step would be impractical at this plate density.

Single End Tab — No Perforations The F-384-100 features a single end tab with no perforations — providing grip during application without requiring tab removal after positioning. The single-tab design keeps application fast and efficient in high-throughput environments where speed of plate sealing is operationally important.

No Heat Sealer Required — Hand or Plate Sealing Roller Application The AlumaSeal® 384™ is applied by hand pressure or with a plate sealing roller — no heat sealing instrument required. A plate sealing roller is recommended for ensuring a complete, uniform seal across all 384 wells, which is more difficult to achieve by hand alone at 384-well density compared to 96-well plates.

AlumaSeal® Format Family — Choosing the Right Foil for Your Plate Format:

Compatible Replacement — Cross-Reference Guide

The AlumaSeal® 384™ F-384-100 is a direct compatible replacement for 384-well aluminum foil plate seals from several major manufacturers. Labs currently using any of the following products can switch directly to the F-384-100 without protocol changes:

• Thermo Fisher Scientific AB-0563 — ABgene® Thermo-Seal Foil for 384-well plates
• 4titude® 4ti-0536/384 — Heat Sealing Foil for 384-well plates
• Axygen® PCR-AS-384 — Aluminum foil seal for 384-well plates
• Bio-Rad MSF1001 — Microseal® 'F' Foil, 384-well format
• Greiner Bio-One 676090 — Universal Sealing Foil, 384-well format

Competitor brand names and catalog numbers are referenced for cross-referencing purposes only. Compatibility should be verified for your specific plates and protocols.

Key Features

• Aluminum foil seal specifically dimensioned for 384-well microplates
• Suitable for both PCR thermal cycling AND cold storage at -80°C
• Pierceable — pipette tips and robotic probes
• No heat sealer required — hand pressure or plate sealing roller
• Single end tab with no perforations — fast, efficient application
• Minimizes evaporation — aluminum foil barrier properties
• Prevents cross-contamination between wells
• Complete light exclusion — opaque aluminum construction
• Certified DNase-free, RNase-free, and nucleic acid-free
• Non-sterile only
• Dimensions: 137.3 × 82.5 mm (including 13.5mm end tab)
• Temperature range: -80°C to +120°C
• Shelf life: 36 months
• 100 foil seals per pack
• Made in the USA

Supported Applications 384-well plate PCR and qPCR sealing, 384-well compound library cold storage at -80°C, high-throughput screening with robotic probe access, automated compound management in 384-well format, genomics and sequencing applications in 384-well format, 384-well plate storage and sample protection, and any 384-well microplate workflow requiring a pierceable aluminum foil seal for both thermal cycling and ultra-low temperature storage.

Technical Specifications