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DNA Clean-Up & Concentration

Zymo Research DNA Clean-Up & Concentration Kits

LIGHT LABS carries the complete Zymo Research line of DNA clean-up and concentration kits — the industry's most trusted and widely cited collection of spin-column and magnetic bead-based DNA purification tools. Whether you're purifying PCR products, removing enzymes and salts from enzymatic reactions, recovering DNA from agarose gels, or concentrating genomic DNA, Zymo Research has a kit engineered for your exact workflow.

DNA Clean & Concentrator (DCC) Kits — PCR Purification in 2 Minutes The DCC family of PCR purification kits utilize a uniquely formulated DNA binding chemistry and novel spin-column design that rapidly purifies ultra-pure DNA from PCR and other enzymatic reactions without the use of hazardous chemicals. Available in four binding capacities — DCC-5 (up to 5 µg), DCC-25 (up to 25 µg), DCC-100 (up to 100 µg), and DCC-500 (up to 500 µg) — the DCC series handles everything from routine PCR cleanup to large-scale restriction digestion purifications. Each kit delivers highly concentrated DNA in a minimum elution volume of just 6 µL with zero buffer carryover.

Zymoclean™ Gel DNA Recovery Kits — Gel Extraction in 15 Minutes The Zymoclean™ Gel DNA Recovery Kits provide rapid, high-yield purification of DNA from TAE/TBE-buffered agarose gels using Zymo-Spin™ technology — no organic solvents or chloroform required. With over 2,100 citations in peer-reviewed literature, the Zymoclean is one of the most validated gel extraction kits in molecular biology. Fragments from 50 bp to 23 kb are recovered with 70–90% efficiency, eluted in as little as 6 µL. Available in uncapped (D4001, D4002) and capped (D4007, D4008) column formats.

Select-a-Size DNA Clean & Concentrator — Precise Fragment Size Selection For applications requiring defined fragment size ranges, the Select-a-Size DNA Clean & Concentrator lets you selectively recover DNA fragments ≥ 50 bp, ≥ 100 bp, ≥ 150 bp, ≥ 200 bp, or ≥ 300 bp — or perform double size selection — simply by adjusting buffer conditions. The entire purification procedure can be performed in as little as 7 minutes for 2 preps , making it ideal for NGS library preparation, cloning, and PCR cleanup where size discrimination is essential.

Why Zymo Research DNA Clean-Up Kits?

  • Minimum elution volumes (≥ 6 µL) for maximum DNA concentration
  • No hazardous chemicals — no phenol, chloroform, or organic denaturants
  • Zero buffer retention columns — no carryover contamination
  • Compatible with crude extracts, enzymatic reactions, and agarose gels
  • Purity: A260/A280 > 1.8; A260/A230 > 1.8
  • Ready-to-use DNA — no additional cleanup steps required
  • Lot-to-lot tested for consistent performance
  • Competitively priced alternatives to QIAGEN, Thermo, and Millipore kits

Supported Applications Across This Category PCR cleanup and purification, gel extraction and band isolation, enzyme and salt removal, DNA desalting and concentration, next-generation sequencing library preparation, DNA ligation, sequencing, restriction endonuclease digestion, radiolabeling, microarray analysis, RNA transcription, and DNA transfection.

Shop the full Zymo Research DNA Clean-Up & Concentration collection below, or contact the LIGHT LABS team at sales@lightlabsusa.com or 1-800-286-3103 for help choosing the right kit for your application.

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