CELLTREAT® 229713 | 500mL Bottle Top Filter, 0.45µm PES, 90mm Diameter, Sterile — No Bottle Included

The CELLTREAT® 229713 is a 500mL bottle top filter with 0.45µm PES membrane — sterile, with a 500mL expanded 90mm diameter membrane that increases flow and reduces clogs for faster filtration, with 44% more filtration area than the previous membrane. The 229713 is the standalone bottle top filter format — designed for labs that already have their own CELLTREAT solution bottles or other standard 45mm threaded bottles and need only the filter component. Bottle top filters fit on CELLTREAT® solution bottles or other standard 45mm threaded solution storage bottles. Bottle top filters do not include solution bottles. Sterile by gamma irradiation. RNase-free, DNase-free, and non-pyrogenic.

⚠️ Critical Distinction — Bottle Top Filter Only. Solution Bottle NOT Included. The 229713 is the bottle top filter component only — it does not include a solution bottle or cap. This is the key difference from the CELLTREAT Filter Systems (229701–229708) which are complete systems including bottle top filter, solution bottle, and cap. The 229713 is the correct choice for labs that:

• Already have CELLTREAT solution bottles or compatible 45mm threaded bottles
• Want to purchase filter tops and bottles separately for cost or inventory flexibility
• Are replacing only the filter component after a bottle has been cleaned and reused
• Prefer to use a specific bottle brand or size not included in the complete filter system packages

For a complete ready-to-use filtration system including solution bottle and cap, see the CELLTREAT 229703 (500mL, 0.45µm PES Filter System).

229713 vs. 229703 — Bottle Top Filter vs. Complete Filter System:

⚠️ Important — 0.45µm Does NOT Provide Sterile Filtration 0.45µm PES membrane is ideal for solution clarification. The 229713 is designed for particle removal, solution clarification, and pre-filtration — not sterile filtration. For sterile filtration at 500mL scale, the 0.22µm version (229717) is the correct product.

Expanded 90mm Membrane — 44% More Filtration Area 500mL filters feature expanded 90mm diameter membrane to increase flow and reduce clogs for faster filtration. 90mm diameter membrane has 44% more filtration area than previous membrane. The expanded 90mm membrane distributes the 500mL particulate load across a wider area — reducing local fouling and clogging, and maintaining high flow rates throughout the complete filtration volume.

0.45µm PES Membrane — High Flow Rate with Low Protein Binding Polyethersulfone (PES) membrane is designed for high flow rate with low binding. The hydrophilic PES membrane wets instantly on contact with aqueous solutions and provides low protein binding — minimizing loss of proteins and biologically active components during clarification.

Easy-to-Read Molded Graduations and Bold Pore Size Identification Easy-to-read molded graduations on bottle top filter. Housings feature boldly printed membrane material and pore size for easy identification. The 0.45µm pore size is boldly printed on the filter housing — critical for preventing accidental use of the clarification filter in applications requiring 0.22µm sterile filtration.

Fits Standard 45mm Threaded Bottles — Broad Compatibility Bottle top filters fit on CELLTREAT® solution bottles or other standard 45mm threaded solution storage bottles. The 229713 is compatible with the full CELLTREAT solution bottle family as well as other standard 45mm threaded bottles from major laboratory suppliers — providing maximum flexibility for labs with existing bottle inventories.

Angled Hose Barb Adapter, Curved Design, and Improved Filter Support Angled hose barb adapter fits three size hose diameters and prevents the filter from tipping. Improved filter support provides faster flow rates. Curved bottle design for easy handling. The angled barb accommodates 6mm, 9mm, and 12mm ID vacuum tubing without adapters, prevents tipping during filtration, and the improved support grid sustains high flow rates throughout the complete 500mL volume.

Lot Number and Expiration Date on Every Bottle Top Printed lot number and expiration date on every bottle top. Full lot traceability for regulated laboratory environments and quality management documentation.

Compatible Replacement — Cross-Reference Guide

The CELLTREAT® 229713 is a direct compatible replacement for 500mL 0.45µm PES standalone bottle top filters from several major manufacturers:

• Millipore® SCGVUSS2RE — Stericup 500mL 0.45µm PES bottle top filter only
• Thermo Fisher Nalgene™ 296-4545 — Nalgene 500mL 0.45µm PES bottle top filter
• VWR® 10040-460 — VWR 500mL 0.45µm PES bottle top filter, no bottle

Competitor brand names and catalog numbers are referenced for cross-referencing purposes only. Compatibility should be verified for your specific bottles and protocol.

Complete CELLTREAT® Bottle Top Filter Family — Key Formats:

Key Features

• 500mL bottle top filter — filter component only, no solution bottle included
• 0.45µm PES membrane — particle removal and solution clarification
• ⚠️ 0.45µm does NOT provide sterile filtration — use 229717 (0.22µm) for sterile applications
• Fits CELLTREAT solution bottles and all standard 45mm threaded solution storage bottles
• Expanded 90mm membrane diameter — 44% more filtration area than previous generation
• Expanded membrane reduces clogging and increases flow for faster filtration
• Hydrophilic PES membrane — high flow rate with low protein binding
• Improved filter support — sustained flow rates under vacuum
• Easy-to-read molded graduations on bottle top filter
• Bold printed membrane material and 0.45µm pore size — easy identification
• Angled hose barb adapter — fits 6mm, 9mm, and 12mm ID tubing, prevents tipping
• Lot number and expiration date printed on every bottle top
• Sterile — gamma irradiation
• RNase-free and DNase-free — certified
• Non-pyrogenic

Supported Applications HPLC mobile phase preparation and sample pre-filtration at 500mL scale, buffer and solution clarification, biological solution particle removal, pre-filtration before 0.22µm sterile filtration, and any 500mL 0.45µm clarification application where a compatible solution bottle is already available.

Technical Specifications