MTC Bio OptiWell™ Tip Comb D3340-08 | 8-Tip V-Bottom Strip, Polypropylene, Non-Sterile — 480/Pack (240 Bags of 2)

The MTC Bio OptiWell™ Tip Comb D3340-08 is an 8-tip V-bottom polypropylene strip tip comb — designed for magnetic bead-based nucleic acid and protein affinity purification in automated extraction systems including KingFisher™ Flex and Accuris IsoPure™ extraction systems. The 8-tip single-row strip format processes one row of 8 wells simultaneously per extraction step — providing the flexibility to process any number of samples from 1 to 8 per strip, or to use multiple strips side by side for mid-size batch processing. Can be used for viral RNA extraction, DNA extraction, immunoprecipitation, and quantification. Made of chemically inert, low binding virgin polypropylene. Certified RNase-free, DNase-free, and pyrogen-free. Non-sterile. Pack of 480 tip combs — 240 bags of 2 per pack. Catalog # D3340-08.

8-Tip Single-Row Strip Format — The Most Flexible Tip Comb Format The 8-tip strip format of the D3340-08 is the most flexible configuration in the OptiWell™ Tip Comb family — processing a single row of 8 wells simultaneously rather than the fixed 24-well or full 96-well formats. The 8-tip strip provides three key workflow advantages:

• Variable batch sizing — process as few as 1 sample or as many as 8 samples per strip, then combine multiple strips for any batch size up to 96 wells (12 strips of 8 = full 96-well plate)
• Row-by-row processing — extract samples row by row across a 96-well plate, adding strips as samples arrive rather than waiting to fill a full 24-well or 96-well batch
• Partial plate flexibility — avoid consuming 24-tip or 96-tip combs when only processing 8 or 16 samples — the 8-tip strip eliminates wasted tips from unused comb positions

For labs with highly variable extraction batch sizes — from a single sample to a full plate — the D3340-08 provides the only tip comb format that matches exactly to any batch size without waste.

D3340-08 vs. D3340-24 vs. D3340-96 — Choosing the Right Tip Comb Format:

480 Tip Combs Per Pack — Maximum Supply for High-Frequency Strip Use Pack of 480 ea (240 bags of 2ea). At 480 tip combs per pack — the largest pack size in the OptiWell™ tip comb lineup — the D3340-08 is specifically formatted for labs that consume 8-tip strips at high frequency. For labs running multiple small-batch extraction runs per day, or processing samples individually and in small groups throughout the day, the 480-pack provides a full working supply that minimizes reorder frequency. At 480 strips per pack, the D3340-08 provides one of the most economical per-strip costs in the OptiWell™ tip comb family — especially for labs that would otherwise be forced to use 24-tip or 96-tip combs for small batches.

KingFisher™ Flex and Accuris IsoPure™ Compatible — 8-Tip Strip Format Compatible with automated systems including KingFisher™ Flex and Accuris IsoPure™ extraction systems. The D3340-08 8-tip strip format is compatible with the strip processing modes of both the KingFisher™ Flex and Accuris IsoPure™ platforms — which support both full-plate and individual strip processing configurations. For labs using KingFisher™ Flex or Accuris IsoPure™ and running variable or small-batch extractions, the D3340-08 strip format provides the correctly sized consumable for strip-mode instrument operation.

V-Bottom Tip Geometry — Complete Bead Collection in Strip Format The V-bottom tip geometry of the D3340-08 is specifically designed to work with V-bottom deep well plates — concentrating magnetic beads at the lowest point of each well for complete bead collection by the magnetic tip strip during the capture step. All 8 tips in each strip engage simultaneously for uniform bead capture across the row — maintaining the same complete recovery performance as the larger 24-tip and 96-tip comb formats in the single-row strip configuration.

Low Binding Virgin Polypropylene — Minimal Sample Loss Per Strip Made of chemically inert, low binding virgin polypropylene. The low binding formulation minimizes non-specific adsorption of nucleic acids, proteins, and magnetic beads to the tip comb surface across all 8 tip positions of each strip. The chemically inert polypropylene material is compatible with the full range of lysis buffers, wash buffers, and elution buffers used in magnetic bead extraction protocols.

Certified RNase-Free, DNase-Free, and Pyrogen-Free Certified RNase, DNase and pyrogen free. The D3340-08 meets the molecular biology grade purity standards required for nucleic acid extraction applications — eliminating the risk of RNA and DNA degradation from nuclease contamination in every strip across the 480-comb pack.

Paired with OptiWell™ Deep Well Plates — Complete Extraction System The D3340-08 8-tip strip comb is designed to work in conjunction with OptiWell™ V-bottom deep well plates. Compatible OptiWell™ V-bottom plate formats include:

Compatible Replacement — Cross-Reference Guide

The MTC Bio OptiWell™ Tip Comb D3340-08 is a compatible alternative to OEM 8-tip strip combs from several major automated extraction instrument manufacturers:

• Thermo Fisher KingFisher™ Flex Tip Comb, 8-tip Strip — OEM 8-tip strip comb for KingFisher™ Flex
• Thermo Fisher KingFisher™ Duo Tip Comb, 8-tip Strip — OEM 8-tip strip comb for KingFisher™ Duo
• Accuris IsoPure™ Tip Comb, 8-tip Strip — OEM 8-tip strip comb for IsoPure™

The D3340-08 is validated as a compatible alternative to OEM tip combs for the listed platforms. Compatibility should be confirmed for your specific instrument firmware version and extraction protocol. Competitor brand names are referenced for cross-referencing purposes only.

Key Features

• MTC Bio OptiWell™ Tip Comb — Catalog # D3340-08
• 8-tip single-row strip format — most flexible tip comb for variable batch sizes
• V-bottom tip geometry — matched for V-bottom deep well plate formats
• Compatible with KingFisher™ Flex and Accuris IsoPure™ extraction systems
• Low binding virgin polypropylene — chemically inert, minimal sample loss
• Certified RNase-free, DNase-free, and pyrogen-free
• Non-sterile
• Pack of 480 tip combs — 240 bags of 2 per pack — largest pack in the OptiWell™ tip comb lineup
• Most economical per-strip cost for small-batch extraction workflows
• Sigma-Aldrich catalog # MTCD334008
• Single-use — discard after each extraction run to prevent cross-contamination
• 24-tip format: D3340-24 / D3340-24S (sterile)
• 96-tip format: D3340-96 / D3340-96S (sterile)

Supported Applications Small-batch magnetic bead-based DNA extraction (1–8 samples per run), variable batch size viral RNA extraction, row-by-row 96-well plate processing for staggered sample arrival workflows, continuous flow extraction for samples processed individually as they arrive, partial plate extraction where only some rows of a 96-well plate are used, immunoprecipitation and protein affinity purification at small scale, nucleic acid quantification sample preparation, and any automated magnetic bead-based extraction workflow requiring maximum batch size flexibility with 8-tip V-bottom strip tip combs for KingFisher™ Flex or Accuris IsoPure™ platforms.

Technical Specifications