MTC Bio OptiWell™ Tip Comb D3340-96 | 96-Tip V-Bottom, Polypropylene, Non-Sterile — 100/Pack (50 Bags of 2)

Product Description

The MTC Bio OptiWell™ Tip Comb D3340-96 is a 96-tip V-bottom polypropylene tip comb — designed for magnetic bead-based nucleic acid and protein affinity purification in automated extraction systems including KingFisher™ Flex and Accuris IsoPure™ extraction systems. Can be used for viral RNA extraction, DNA extraction, immunoprecipitation, and quantification. Made of chemically inert, low binding virgin polypropylene. Certified RNase-free, DNase-free, and pyrogen-free. Non-sterile. Pack of 100 tip combs — 50 bags of 2 per pack. Catalog # D3340-96.

D3340-96 vs. D3340-24 — 96-Tip vs. 24-Tip: Choosing the Right Format The D3340-96 and D3340-24 are identical OptiWell™ V-bottom tip combs in every way — the number of tips and pack quantity are the sole differences:

The D3340-96 is the correct choice for labs running full 96-well plate extraction workflows — processing up to 96 samples simultaneously per extraction run on KingFisher™ Flex or Accuris IsoPure™ platforms. For smaller batch sizes of 24 samples or fewer, the D3340-24 is the appropriate format.

96-Tip Format — Full Plate Throughput for High-Volume Extraction The 96-tip format of the D3340-96 processes all 96 samples of a standard deep well plate simultaneously per extraction run — the maximum throughput format for automated magnetic bead extraction workflows. For high-volume genomics labs, core extraction facilities, and any environment where sample throughput is the primary constraint, the D3340-96 enables processing of an entire 96-well plate in a single automated run — dramatically reducing the number of runs required per day compared to the 24-tip format. At 100 tip combs per pack, the D3340-96 also provides the largest available supply format — minimizing reorder frequency for high-throughput labs.

V-Bottom Tip Geometry — Optimized for V-Bottom Deep Well Plates The V-bottom tip geometry of the D3340-96 is specifically designed to work with V-bottom deep well plates — concentrating magnetic beads at the lowest point of each well for complete bead collection by the magnetic tip array during the capture step. The V-bottom tip profile matches the conical geometry of the well bottom to minimize the gap between tip and well base — ensuring complete bead capture from all 96 wells simultaneously in a single magnetic engagement. For full-plate extraction workflows using OptiWell™ V-bottom deep well plates across all 96 wells, the D3340-96 is the correctly matched 96-tip consumable.

KingFisher™ Flex and Accuris IsoPure™ Compatible — Full Plate Format Compatible with automated systems including KingFisher™ Flex and Accuris IsoPure™ extraction systems. The D3340-96 OptiWell™ Tip Comb provides full 96-well plate throughput on both the KingFisher™ Flex (the most widely deployed automated magnetic bead extraction platform) and the Accuris IsoPure™ system — enabling complete plate processing in a single automated run at a lower per-run consumable cost than OEM tip combs from these instrument manufacturers.

Low Binding Virgin Polypropylene — Minimal Sample Loss Across All 96 Tips Made of chemically inert, low binding virgin polypropylene. The low binding formulation minimizes non-specific adsorption of nucleic acids, proteins, and magnetic beads to the tip comb surface across all 96 tip positions simultaneously — ensuring consistent, high-yield extraction performance from every well position on the plate. The chemically inert polypropylene material is compatible with the full range of lysis buffers, wash buffers, and elution buffers used in 96-well magnetic bead extraction protocols without leaching contaminants.

Certified RNase-Free, DNase-Free, and Pyrogen-Free Certified RNase, DNase and pyrogen free. The D3340-96 meets the molecular biology grade purity standards required for nucleic acid extraction applications across all 96 tip positions — eliminating the risk of RNA and DNA degradation from nuclease contamination. For high-throughput viral RNA extraction and RNA-seq library preparation workflows where RNA integrity across all 96 samples is critical, the RNase-free certification is essential.

100 Pack — Maximum Supply for High-Throughput Labs Pack of 100 ea (50 bags of 2ea). At 100 tip combs per pack — double the 50-comb pack of the D3340-24 — the D3340-96 is specifically formatted for high-throughput labs that consume tip combs at high frequency. For labs running multiple 96-sample extraction batches per day, the 100-pack format reduces reorder frequency and per-comb packaging overhead compared to smaller pack formats. The 2-per-bag packaging ensures tip combs are stored in a sealed, protected environment until use.

Paired with OptiWell™ Deep Well Plates — Complete Extraction System The D3340-96 tip comb is designed to work in conjunction with OptiWell™ 96-well V-bottom deep well plates as a complete automated extraction system. Compatible OptiWell™ plate formats for V-bottom tip comb applications:

Compatible Replacement — Cross-Reference Guide

The MTC Bio OptiWell™ Tip Comb D3340-96 is a compatible alternative to OEM 96-tip combs from several major automated extraction instrument manufacturers:

• Thermo Fisher KingFisher™ Flex Tip Comb, 96-tip (97003534) — OEM 96-tip comb for KingFisher™ Flex
• Thermo Fisher KingFisher™ Duo Prime Tip Comb, 96-tip — OEM 96-tip comb for KingFisher™ Duo Prime
• Accuris IsoPure™ Tip Comb, 96-tip — OEM 96-tip comb for IsoPure™

The D3340-96 is validated as a compatible alternative to OEM tip combs for the listed platforms. Compatibility should be confirmed for your specific instrument firmware version and extraction protocol. Competitor brand names are referenced for cross-referencing purposes only.

Key Features

• MTC Bio OptiWell™ Tip Comb — Catalog # D3340-96
• 96-tip format — full plate throughput, processes all 96 samples simultaneously
• V-bottom tip geometry — matched for V-bottom deep well plate formats
• Compatible with KingFisher™ Flex and Accuris IsoPure™ extraction systems
• Low binding virgin polypropylene — chemically inert, minimal sample loss across all 96 tips
• Certified RNase-free, DNase-free, and pyrogen-free
• Non-sterile
• Pack of 100 tip combs — 50 bags of 2 per pack
• Largest available pack size — maximum supply for high-throughput labs
• Sigma-Aldrich catalog # MTCD334096
• Single-use — discard after each extraction run to prevent cross-contamination
• 24-tip format available: D3340-24

Supported Applications High-throughput magnetic bead-based DNA extraction from full 96-well plates, high-throughput viral RNA extraction, total RNA extraction from biological samples at 96-sample scale, immunoprecipitation and protein affinity purification in full plate format, nucleic acid quantification sample preparation, cell-free DNA and cfRNA extraction at high throughput, SARS-CoV-2 and other viral nucleic acid extraction in high-volume settings, environmental sample nucleic acid extraction, food safety nucleic acid testing at 96-sample scale, pharmaceutical QC nucleic acid extraction, core laboratory extraction services, and any automated magnetic bead-based extraction workflow requiring 96-tip V-bottom tip combs for KingFisher™ Flex or Accuris IsoPure™ platforms at maximum throughput.

Technical Specifications