MTC Bio OptiWell™ Tip Comb D3340-08S | 8-Tip V-Bottom Strip, Polypropylene, Sterile — 480/Pack (240 Bags of 2)

The MTC Bio OptiWell™ Tip Comb D3340-08S is a sterile 8-tip V-bottom polypropylene strip tip comb — designed for magnetic bead-based nucleic acid and protein affinity purification in automated extraction systems including KingFisher™ Flex and Accuris IsoPure™ extraction systems. The 8-tip single-row strip format processes one row of 8 wells simultaneously per extraction step — providing the flexibility to process any number of samples from 1 to 8 per strip in a validated sterile format. Can be used for viral RNA extraction, DNA extraction, immunoprecipitation, and quantification. Made of chemically inert, low binding virgin polypropylene. Certified RNase-free, DNase-free, and pyrogen-free. Sterile. Pack of 480 tip combs — 240 bags of 2 per pack. Catalog # D3340-08S.

D3340-08S vs. D3340-08 — Sterile vs. Non-Sterile: The Only Difference The D3340-08S and D3340-08 are identical OptiWell™ 8-tip V-bottom strip tip combs in every way — sterility is the sole difference:

The D3340-08S sterile format is the correct choice for labs whose small-batch or row-by-row strip extraction workflows require validated sterile consumables — including sterile clinical nucleic acid extraction of small patient cohorts, GMP-compliant pharmaceutical testing in strip format, and any regulated application where sterile strip tip combs are specified in the SOP. For standard research workflows where sterility is not required, the more economical D3340-08 is the appropriate choice.

D3340-08S vs. D3340-24S vs. D3340-96S — Choosing the Right Sterile Format:

The D3340-08S is the correct sterile choice for labs running variable or small sterile extraction batches — from a single clinical sample to a full row of 8 — where the 24-tip or 96-tip sterile formats would result in unused tip positions being wasted.

8-Tip Single-Row Strip — Maximum Flexibility in Sterile Format The 8-tip strip format of the D3340-08S provides the same workflow flexibility as the non-sterile D3340-08 — now in validated sterile format:

• Variable sterile batch sizing — process as few as 1 or as many as 8 samples per sterile strip without wasting unused tips from larger comb formats
• Row-by-row sterile processing — extract sterile samples row by row across a 96-well plate as they arrive, maintaining sterility throughout the workflow
• Partial plate sterile flexibility — run sterile partial-plate extractions without consuming 24-tip or 96-tip sterile combs for small batches

When Sterile 8-Tip Strip Combs Are Required The D3340-08S is specifically needed in regulated application contexts where both the 8-tip strip format and sterility are simultaneously required:

• Clinical labs processing small patient cohorts — sterile extraction of 1–8 patient samples per run in a validated sterile strip format
• GMP pharmaceutical QC in strip format — regulated testing workflows at small sample batch sizes requiring sterile consumables throughout
• Cell-free nucleic acid extraction at small scale — sterile cfDNA and cfRNA extraction from individual or small groups of patient plasma samples
• Sterile method validation — validating sterile strip-format extraction SOPs at 8-sample scale
• Continuous sterile flow workflows — processing individual sterile samples as they arrive throughout the day using one strip at a time

V-Bottom Tip Geometry — Complete Sterile Bead Collection The V-bottom tip geometry of the D3340-08S concentrates magnetic beads at the lowest point of each well for complete bead collection — maintaining the same recovery performance as the D3340-08 in a sterile format. Compatible sterile OptiWell™ V-bottom plate formats:

480 Pack — Maximum Sterile Supply for High-Frequency Strip Use Pack of 480 ea (240 bags of 2ea). At 480 sterile tip combs per pack — matching the pack size of the non-sterile D3340-08 — the D3340-08S provides the largest available sterile tip comb supply in the OptiWell™ lineup. For sterile labs running multiple small-batch extraction runs per day, the 480-pack minimizes reorder frequency while maintaining a fully sterile supply. The 2-per-bag packaging ensures each sterile strip is protected in its individual sealed bag until use.

KingFisher™ Flex and Accuris IsoPure™ Compatible — Sterile 8-Tip Strip Format Compatible with automated systems including KingFisher™ Flex and Accuris IsoPure™ extraction systems. The D3340-08S provides a validated sterile alternative to OEM sterile 8-tip strip combs from these instrument manufacturers — maintaining full instrument compatibility in strip processing mode while offering competitive pricing for sterile strip consumables.

Low Binding Virgin Polypropylene — Sterile and Chemically Inert Made of chemically inert, low binding virgin polypropylene. The sterile D3340-08S maintains the same low binding surface properties as the non-sterile D3340-08 — gamma irradiation sterilization does not compromise the low binding characteristics of the polypropylene material across all 8 tip positions of each strip.

Certified RNase-Free, DNase-Free, and Pyrogen-Free Certified RNase, DNase and pyrogen free. The D3340-08S carries the same nuclease-free and pyrogen-free certifications as the D3340-08 — in addition to validated sterility — across all 480 sterile tip combs in the pack.

Compatible Replacement — Cross-Reference Guide

The MTC Bio OptiWell™ Tip Comb D3340-08S is a compatible alternative to sterile OEM 8-tip strip combs from several major automated extraction instrument manufacturers:

• Thermo Fisher KingFisher™ Flex Tip Comb, 8-tip Strip, Sterile — OEM sterile 8-tip strip comb for KingFisher™ Flex
• Thermo Fisher KingFisher™ Duo Tip Comb, 8-tip Strip, Sterile — OEM sterile 8-tip strip comb for KingFisher™ Duo
• Accuris IsoPure™ Tip Comb, 8-tip Strip, Sterile — OEM sterile 8-tip strip comb for IsoPure™

The D3340-08S is validated as a compatible sterile alternative to OEM tip combs for the listed platforms. Compatibility should be confirmed for your specific instrument firmware version and extraction protocol. Competitor brand names are referenced for cross-referencing purposes only.

Key Features

• MTC Bio OptiWell™ Tip Comb — Catalog # D3340-08S
• 8-tip single-row strip format — maximum sterile flexibility for variable batch sizes
• V-bottom tip geometry — matched for V-bottom deep well plate formats
• Sterile — gamma irradiation validated sterility
• Compatible with KingFisher™ Flex and Accuris IsoPure™ extraction systems in strip processing mode
• Low binding virgin polypropylene — chemically inert, minimal sample loss
• Certified RNase-free, DNase-free, and pyrogen-free
• Pack of 480 sterile tip combs — 240 bags of 2 per pack — largest sterile tip comb pack in the OptiWell™ lineup
• Sigma-Aldrich catalog # MTCD334008S
• Single-use — discard after each extraction run to prevent cross-contamination
• Non-sterile 8-tip version: D3340-08
• Sterile 24-tip version: D3340-24S
• Sterile 96-tip version: D3340-96S

Supported Applications Sterile small-batch magnetic bead-based DNA extraction (1–8 samples per run), sterile viral RNA extraction from individual and small groups of samples, sterile row-by-row 96-well plate processing for staggered sterile sample arrival workflows, sterile continuous flow extraction for clinical samples processed individually as they arrive, sterile partial plate extraction, sterile cfDNA and cfRNA liquid biopsy extraction from small patient cohorts, sterile immunoprecipitation and protein affinity purification at small scale, GMP pharmaceutical nucleic acid QC testing in strip format, and any automated magnetic bead-based extraction workflow requiring maximum sterile batch size flexibility with 8-tip V-bottom strip tip combs for KingFisher™ Flex or Accuris IsoPure™ platforms.

Technical Specifications