CELLTREAT® 229704 | 1000mL Vacuum Filter System, 0.45µm PES Membrane, Sterile — 12/Case

Product Description

The CELLTREAT® 229704 is a complete 1000mL sterile vacuum filter system — bottle top filter with 0.45µm PES membrane, 1000mL solution bottle, and HDPE screw cap — designed for large-volume vacuum filtration where particle removal, solution clarification, and pre-filtration of up to 1000mL are required without a full sterile filtration requirement. 0.45µm PES membrane ideal for solution clarification. The polyethersulfone (PES) membrane provides high flow rate with low protein binding across the full 1000mL filtration volume. Filter systems include bottle top filter and solution bottle with cap. Sterile by gamma irradiation. RNase-free, DNase-free, and non-pyrogenic. Shelf life: 36 months. 12 filter systems per case, individually packaged.

⚠️ Important — 0.45µm Does NOT Provide Sterile Filtration The 229704 0.45µm filter is designed for solution clarification and particle removal at 1000mL scale — not sterile filtration. For sterile filtration of cell culture media and buffers at 1000mL scale, the 0.22µm 229708 is the correct product. The 229704 is appropriate for large-volume HPLC mobile phase preparation, solution pre-filtration, buffer clarification, and any 1000mL application where removal of particles ≥0.45µm is required without a sterility requirement.

229704 vs. 229708 — Choosing the Right Pore Size for 1000mL Filtration:

0.45µm PES Membrane — Maximum Flow Rate for Large-Volume Clarification Polyethersulfone (PES) membrane is designed for high flow rate with low binding. The 0.45µm pore size presents significantly less hydraulic resistance than a 0.22µm membrane — delivering the fastest possible flow rates for 1000mL clarification workflows under standard vacuum. The inherently hydrophilic and low protein binding PES surface minimizes loss of proteins and biologically active components during filtration — making the 229704 well-suited for clarifying large volumes of protein solutions, enzyme preparations, and biological buffers where both throughput and sample recovery are important.

90mm Membrane Diameter — Maximum Filtration Surface for 1000mL Scale The 90mm membrane diameter of the 229704 provides the maximum filtration surface area available in the CELLTREAT filter system line — distributing the full 1000mL particulate load across a wide membrane area to reduce local fouling and clogging. For large-volume clarification of particulate-rich solutions, the 90mm membrane makes the difference between a complete filtration run and a prematurely clogged membrane that requires a second filter unit to complete.

Easy-to-Read Molded Graduations — Visual Volume Monitoring at 1000mL Scale Easy-to-read molded graduations on bottle top filter. Molded graduation markings on the bottle top filter funnel allow real-time visual monitoring of filtration progress across the full 1000mL volume — confirming that filtration is proceeding and tracking how much volume remains to be filtered.

Bold Membrane Identification Printing — 0.45µm Clearly Marked Housings feature boldly printed membrane material and pore size for easy identification. The 0.45µm pore size is boldly printed on the filter housing — critical in labs where both 229704 (0.45µm) and 229708 (0.22µm) 1000mL filters are stocked together. Using the wrong pore size at 1000mL scale is a particularly costly error — the bold identification prevents this mistake.

Angled Hose Barb Adapter — Fits Three Tubing Sizes, Prevents Tipping Angled hose barb adapter fits three size hose diameters and prevents the filter from tipping. The angled barb accommodates 6mm, 9mm, and 12mm ID vacuum tubing without adapters and prevents the filter system from tipping — especially important at 1000mL scale where a fully loaded bottle is significantly heavier than smaller formats.

Curved Bottle Design and Improved Filter Support Curved bottle design for easy handling. Improved filter support provides faster flow rates. The curved bottle profile provides ergonomic handling of the large-volume bottle, while the improved filter support grid maintains membrane geometry under vacuum for sustained high flow rates throughout the full 1000mL filtration.

Lot Number and Expiration Date on Every Bottle Top Printed lot number and expiration date on every bottle top. Full lot traceability for regulated laboratory environments and quality management documentation.

Complete System — Filter, Bottle, and Cap All Included Filter Systems include bottle top filter and solution bottle with cap. The 229704 is supplied as a complete, ready-to-use system — sterile bottle top filter, 1000mL solution bottle, and HDPE screw-on cap all included and individually packaged.

Compatible Replacement — Cross-Reference Guide

The CELLTREAT® 229704 is a direct compatible replacement for 1000mL 0.45µm PES vacuum filter systems from several major manufacturers:

• Millipore® SCHVU10RE — Stericup 1000mL 0.45µm PES filter system, sterile
• Thermo Fisher Nalgene™ 450-0045 — Nalgene Rapid-Flow 1000mL 0.45µm PES filter, sterile
• VWR® 10040-444 — VWR 1000mL 0.45µm PES bottle top filter system, sterile

Competitor brand names and catalog numbers are referenced for cross-referencing purposes only. Compatibility should be verified for your specific application and protocol.

Complete CELLTREAT® Filter System Family — Confirmed:

Key Features

• Complete 1000mL vacuum filter system — bottle top filter, solution bottle, and HDPE cap included
• 0.45µm PES membrane — particle removal and solution clarification at 1000mL scale
• ⚠️ 0.45µm does NOT provide sterile filtration — use 229708 (0.22µm, 1000mL) for sterile applications
• 90mm membrane diameter — maximum filtration surface area for large-volume clarification
• High flow rate with low protein binding PES membrane
• Improved filter support — sustained flow rates under vacuum
• Easy-to-read molded graduations on bottle top filter
• Bold printed membrane material and 0.45µm pore size — easy identification, prevents mix-up with 229708
• Curved bottle design — ergonomic handling of large-volume bottle
• Angled hose barb adapter — fits 6mm, 9mm, and 12mm ID tubing, prevents tipping
• Lot number and expiration date printed on every bottle top
• Polystyrene bottle and funnel / HDPE screw cap
• RNase-free and DNase-free — certified
• Non-pyrogenic
• Sterile — gamma irradiation
• Individually packaged
• Shelf life: 36 months
• 12 filter systems per case

Supported Applications Large-volume HPLC mobile phase preparation and sample pre-filtration at 1000mL scale, large-volume buffer and solution clarification, biological solution particle removal prior to analysis or storage, pre-filtration before 0.22µm sterile filtration, removal of yeast and large particles from 1000mL solutions, and any laboratory application requiring 0.45µm vacuum filtration of up to 1000mL volume.

Technical Specifications